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HIRE (High Intensity REduction), a New Dark Fluid T2-weighted Sequence

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MR Technique: Scans were acquired at 3 T (Siemens Verio) using a FLAIR SPACE (3D) sequence (A), and a HIRE SPACE (3D) sequence (B, C) (Note: HIRE SPACE sequence is a Work in Progress package). Sagittal scans of the brain in a normal volunteer, off-midline, are presented. The FLAIR SPACE scan was acquired in 6:56 min:sec, with an isotropic voxel size of 1 x 1 x 1 mm3. The HIRE SPACE scan was acquired in 4:08 min:sec, with a voxel size of 1 x 0.9 x 1.2 mm3. Two sets of T2-weighted images were acquired using the HIRE SPACE sequence, with echo times of 192 msec (C) and 561 msec (not shown). In a fully automatic post-processing step an additional image with FLAIR-like contrast (B) was generated from this data. Imaging Findings: HIRE is a pulse sequence that allows reconstruction of images with various contrast from a single scan acquisition. In the application illustrated, a single HIRE scan has been acquired, with the displayed result being a T2-weighted scan and a scan with FLAIR-like contrast. Two scans are acquired initially by the sequence, a T2-weighted scan as might be used in clinical practice, and a heavily T2-weighted (or “CSF-only”) scan. These two scans are then used in an fully automatic post-processing procedure to calculate a FLAIR-like scan, in which there is moderate to heavy T2-weighting, but with CSF suppression. The advantage clinically would be the ability to acquire both types of tissue contrast using a single scan, with a net reduction in acquisition time when compared to the two scans acquired separately. Acknowledgment: these scans were acquired with the assistance of Dominik Paul and Katrin Wohlfarth of Siemens AG Healthcare Sector.

 

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