Magnetic resonance contrast agents, in particular the gadolinium-based agents, are very safe and lack the
nephrotoxicity (when injected intravenously) associated with iodinated contrast media. Minor adverse effects occur
infrequently and include nausea, taste perversion, and hives. Whereas these agents cannot be differentiated on the
basis of mild adverse effects, they do differ in regard to chelate stability, with clinical lab abnormalities known with
the less stable agents. The issue of nephrogenic systemic fibrosis (NSF) and its relationship to the gadolinium
chelates, and specifically their in vivo stability, is discussed in depth in the text that follows, together with
recommendations for clinical practice.
Contrast Agents: Safety Profile
Contrast Media Manuals:
Use, Adverse Effects, Treatment of Contrast Reactions
Contrast Agents: Overview
Contrast Agents: Nephrogenic Systemic Fibrosis (NSF)
Contrast Agents: Safety Profile
| Title | View / Download |
| Contrast Agents: Safety Profile |
| Title | View |
| Allergic Reactions to Gadolinium Chelates by Val M. Runge, M.D. |
Contrast Media Manuals:
Use, Adverse Effects, Treatment of Contrast Reactions
| Title | View / Download |
The ESUR Manual on Contrast Media |
| Title | View |
| The ACR Manual on Contrast Media |
| Title | View |
|
Recognition and treatment of acute contrast reactions. William H. Bush Jr., MD, FACR, and Arthur J. Segal, MD, FACR. Reprinted from Applied Radiology, Vol. 38, No. 12, Pages 16-21, Copyright 2009, with permission from Anderson Publishing Ltd. www.appliedradiology.com. |
Contrast Agents: Overview
| Title | View / Download |
| Gadolinium Chelates with Extracellular Distribution | |
| Gadolinium Chelates with Protein Binding |
Contrast Agents: Nephrogenic Systemic Fibrosis (NSF)
| Title | View |
| Contrast Agents: Update on NSF by Henrik S. Thomsen M.D. |
| Title | View |
| Latest on Nephrogenic Systemic Fibrosis (NSF) by Val M. Runge, M.D. |
| Title | View |
| Updates regarding GE, Omniscan, and Henrik Thomsen, MD Lawsuits |
| Title | View |
| Update on GE, Omniscan, and NSF, Jeff Gerth |
| Title | View |
| Contrast Agents: Optimized Contrast Enhanced MRI Protocols in Neuroimaging by Marco Essig M.D. Ph.D. |
| Title | View |
| Improved Contrast Enhancement in MRI of the CNS Using MultiHance by Val M. Runge, M.D. |
| Title | View |
| Optimization of Contrast-enhanced MRA by Ulrike I Attenberger, M.D. |
| Title | View |
| Continuous Table Movement in MR Angiography - syngo Tim CT by Harald Kramer, MD |
Clinical MRI by Val M. Runge, MD
Contrast Media Updates
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