Investigative Radiology
March 2010 (featured article)
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Double Inversion Recovery
Objective: Doube inversion recovery (DIR) is increasingly used in clinical studies on multiple sclerosis, as it selectively images gray matter and lesions. The inversion times used in literature differ significantly from theoretical predictions. One explanation for this are incidental magnetic transfer (iMT) effects, which are caused by the high density of pulses. In this work, the influence of iMT on DIR was analyzed and compared with theoretical assumptions and inversion times found in literature.